Efeitos da melatonina no tratamento de doenças cardiovasculares: o progresso no último ano



Numerosos estudos têm sugerido que a melatonina tem um papel importante em várias doenças cardiovasculares. Os estudos examinados neste artigo científico, mostraram que a melatonina tem um efeito significativo no dano por isquemia-reperfusão, hipertensão pulmonar, hipertensão, doença cardíaca valvular, doença vascular, e o metabolismo lipídico. A melatonina pode ser uma nova opção terapêutica para o tratamento de doenças cardiovasculares.

Effects of melatonin on cardiovascular diseases: progress in the past year.
Curr Opin Lipidol. 2016 Apr 12;
Authors: Sun H, Gusdon AM, Qu S

Abstract
PURPOSE OF REVIEW: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland. Numerous studies have suggested that melatonin plays an important role in various cardiovascular diseases. In this article, recent progress regarding melatonin's effects on cardiovascular diseases is reviewed.
RECENT FINDINGS: In the past year, studies have focused on the mechanism of protection of melatonin on cardiovascular diseases, including myocardial ischemia-reperfusion injury, myocardial hypoxia-reoxygenation injury, pulmonary hypertension, hypertension, atherosclerosis, valvular heart diseases, and other cardiovascular diseases.
SUMMARY: Studies have demonstrated that melatonin has significant effects on ischemia-reperfusion injury, myocardial chronic intermittent hypoxia injury, pulmonary hypertension, hypertension, valvular heart diseases, vascular diseases, and lipid metabolism. As an inexpensive and well tolerated drug, melatonin may be a new therapeutic option for cardiovascular disease.

PMID: 27075419 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/27075419?dopt=Abstract







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